Azarova AM, Gautam G and George RE, ‘Emerging Importance of ALK in Neuroblastoma’ (2011) 21 Seminars in Cancer Biology 267
Beierle EA, ‘MYCN, Neuroblastoma and Focal Adhesion Kinase (FAK)’ 3 Frontiers in bioscience (Elite edition) <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171213/>
Bell E and others, ‘MYCN Oncoprotein Targets and Their Therapeutic Potential’ (2010) 293 Cancer Letters 144
Bender S and others, ‘Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas’ (2013) 24 Cancer Cell 660
Berry T and others, ‘The ALKF1174L Mutation Potentiates the Oncogenic Activity of MYCN in Neuroblastoma’ (2012) 22 Cancer Cell 117
Bleggi-Torres LF and others, ‘Accuracy of the Smear Technique in the Cytological Diagnosis of 650 Lesions of the Central Nervous System’ (2001) 24 Diagnostic Cytopathology 293
Blümcke I and others, ‘Low-Grade Epilepsy-Associated Neuroepithelial Tumours — the 2016 WHO Classification’ (2016) 12 Nature Reviews Neurology 732
Brodeur GM, ‘Neuroblastoma: Biological Insights into a Clinical Enigma’ (2003) 3 Nature Reviews Cancer 203
Brodeur GM and Bagatell R, ‘Mechanisms of Neuroblastoma Regression’ (2014) 11 Nature Reviews Clinical Oncology 704
Brown CE and others, ‘Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy’ (2016) 375 New England Journal of Medicine 2561
Buckner T, Blatt J and Smith SV, ‘The Autopsy in Pediatrics and Pediatric Oncology: A Single-Institution Experience’ (2006) 9 Pediatric and Developmental Pathology 374
Burkhart CA and others, ‘Effects of MYCN Antisense Oligonucleotide Administration on Tumorigenesis in a Murine Model of Neuroblastoma’ (2003) 95 JNCI Journal of the National Cancer Institute 1394
Chen L and others, ‘P53 Is a Direct Transcriptional Target of MYCN in Neuroblastoma’ (2010) 70 Cancer Research 1377
Chhabda S and others, ‘The 2016 World Health Organization Classification of Tumours of the Central Nervous System: What the Paediatric Neuroradiologist Needs to Know’ (2016) 6 Quantitative Imaging in Medicine and Surgery 486
‘Children’s Cancer Statistics | Cancer Research UK’ <http://www.cancerresearchuk.org/health-professional/cancer-statistics/childrens-cancers>
Cossu I and others, ‘Neuroblastoma-Targeted Nanocarriers Improve Drug Delivery and Penetration, Delay Tumor Growth and Abrogate Metastatic Diffusion’ (2015) 68 Biomaterials 89
Ellison DW and others, ‘β-Catenin Status Predicts a Favorable Outcome in Childhood Medulloblastoma: The United Kingdom Children’s Cancer Study Group Brain Tumour Committee’ (2005) 23 Journal of Clinical Oncology 7951
Evans AE, Baum E and Chard R, ‘Do Infants with Stage IV-S Neuroblastoma Need Treatment?’ (1981) 56 Archives of Disease in Childhood 271
Fisher J and others, ‘Avoidance of On-Target Off-Tumor Activation Using a Co-Stimulation-Only Chimeric Antigen Receptor’ (2017) 25 Molecular Therapy 1234
Garrett M. Brodeur, Robert C. Seeger, Manfred Schwab, Harold E. Varmus and J. Michael Bishop, ‘Amplification of N-Myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage’ (1984) 224 Science 1121 <http://www.jstor.org/stable/1692440>
Ghorashian S, Amrolia P and Veys P, ‘Open Access? Widening Access to Chimeric Antigen Receptor (CAR) Therapy for ALL’ (2018) 66 Experimental Hematology 5
Gibson P and others, ‘Subtypes of Medulloblastoma Have Distinct Developmental Origins’ (2010) 468 Nature 1095
Goschzik T and others, ‘Genomic Alterations of Adamantinomatous and Papillary Craniopharyngioma’ [2017] Journal of Neuropathology & Experimental Neurology
Greaves MF and Wiemels J, ‘Origins of Chromosome Translocations in Childhood Leukaemia’ (2003) 3 Nature Reviews Cancer 639
Guglielmi L and others, ‘MYCN Gene Expression Is Required for the Onset of the Differentiation Programme in Neuroblastoma Cells’ (2014) 5 Cell Death & Disease e1081
Gump JM and others, ‘Identification of Targets for Rational Pharmacological Therapy in Childhood Craniopharyngioma’ (2015) 3 Acta Neuropathologica Communications
Hanahan D and Weinberg RA, ‘The Hallmarks of Cancer’ (2000) 100 Cell 57
Hanahan D and Weinberg RA, ‘Hallmarks of Cancer: The Next Generation’ (2011) 144 Cell 646
Hashizume R and others, ‘Pharmacologic Inhibition of Histone Demethylation as a Therapy for Pediatric Brainstem Glioma’ (2014) 20 Nature Medicine 1394
Hasle H and Niemeyer CM, ‘Advances in the Prognostication and Management of Advanced MDS in Children’ (2011) 154 British Journal of Haematology 185
Hill RM and others, ‘Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease’ (2015) 27 Cancer Cell 72
Hourigan CS and Karp JE, ‘Minimal Residual Disease in Acute Myeloid Leukaemia’ (2013) 10 Nature Reviews Clinical Oncology 460
Huang M and Weiss WA, ‘Neuroblastoma and MYCN’ (2013) 3 Cold Spring Harbor Perspectives in Medicine a014415
Huber K, Kalcheim C and Unsicker K, ‘The Development of the Chromaffin Cell Lineage from the Neural Crest’ (2009) 151 Autonomic Neuroscience 10
Hubert CG and others, ‘A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found’ (2016) 76 Cancer Research 2465
Hunger SP and Mullighan CG, ‘Acute Lymphoblastic Leukemia in Children’ (2015) 373 New England Journal of Medicine 1541
International Agency for Research on Cancer, WHO Classification of Tumours of the Central Nervous System (David N Louis and others eds, Revised 4th edition, International Agency for Research on Cancer 2016)
Johnson LA and June CH, ‘Driving Gene-Engineered T Cell Immunotherapy of Cancer’ (2017) 27 Cell Research 38
Kirsti Sirkiä, Ulla M. Saarinen‐Pihkala, Liisa Hovi, Hannu Sariola, ‘Autopsy in Children with Cancer Who Die While in Terminal Care’ (1998) 30 Medical and Pediatric Oncology 284 <https://onlinelibrary.wiley.com/doi/abs/10.1002/(SICI)1096-911X(199805)30:5%3C284::AID-MPO4%3E3.0.CO;2-B>
Klebanoff CA, Rosenberg SA and Restifo NP, ‘Prospects for Gene-Engineered T Cell Immunotherapy for Solid Cancers’ (2016) 22 Nature Medicine 26
Koebel CM and others, ‘Adaptive Immunity Maintains Occult Cancer in an Equilibrium State’ (2007) 450 Nature 903
Korshunov, AndreySturm, DominikRyzhova, MarinaHovestadt, VolkerGessi, Marco, ‘Embryonal Tumor with Abundant Neuropil and True Rosettes (ETANTR), Ependymoblastoma, and Medulloepithelioma Share Molecular Similarity and Comprise a Single Clinicopathological Entity’ 128 Acta Neuropathologica 279 <https://search.proquest.com/docview/1545765655?OpenUrlRefId=info:xri/sid:primo&accountid=14511>
Kotrova M and others, ‘Is Next-Generation Sequencing the Way to Go for Residual Disease Monitoring in Acute Lymphoblastic Leukemia?’ (2017) 21 Molecular Diagnosis & Therapy 481
Larson JD and others, ‘Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression’ [2018] Cancer Cell
Lee TI and Young RA, ‘Transcriptional Regulation and Its Misregulation in Disease’ (2013) 152 Cell 1237
Lewis PW and others, ‘Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma’ (2013) 340 Science 857
Liu Z and Thiele CJ, ‘ALK and MYCN: When Two Oncogenes Are Better than One’ (2012) 21 Cancer Cell 325
Lord CJ and Ashworth A, ‘Biology-Driven Cancer Drug Development: Back to the Future’ (2010) 8 BMC Biology
Lu B and others, ‘Wnt Drug Discovery: Weaving Through the Screens, Patents and Clinical Trials’ (2016) 8 Cancers
Mackall CL, Merchant MS and Fry TJ, ‘Immune-Based Therapies for Childhood Cancer’ (2014) 11 Nature Reviews Clinical Oncology 693
Majzner RG, Heitzeneder S and Mackall CL, ‘Harnessing the Immunotherapy Revolution for the Treatment of Childhood Cancers’ (2017) 31 Cancer Cell 476
Marabelle A and others, ‘Hypercalcemia and 13- -Retinoic Acid in Post-Consolidation Therapy of Neuroblastoma’ (2009) 52 Pediatric Blood & Cancer 280
Martinez-Barbera JP and Andoniadou CL, ‘Concise Review: Paracrine Role of Stem Cells in Pituitary Tumors: A Focus on Adamantinomatous Craniopharyngioma’ (2016) 34 STEM CELLS 268
Martinez-Barbera JP and Buslei R, ‘Adamantinomatous Craniopharyngioma: Pathology, Molecular Genetics and Mouse Models’ (2015) 28 Journal of Pediatric Endocrinology and Metabolism
Matthay KK and others, ‘Treatment of High-Risk Neuroblastoma with Intensive Chemotherapy, Radiotherapy, Autologous Bone Marrow Transplantation, and 13- -Retinoic Acid’ (1999) 341 New England Journal of Medicine 1165
Milne TA, ‘Mouse Models of MLL Leukemia: Recapitulating the Human Disease’ (2017) 129 Blood 2217
Morsut L and others, ‘Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors’ (2016) 164 Cell 780
Mossé YP and others, ‘Identification of ALK as a Major Familial Neuroblastoma Predisposition Gene’ (2008) 455 Nature 930
Nataliya Zhukova, ‘Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma’ (2013) 31 Journal of Clinical Oncology <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878050/>
‘Nature Reviews Immunology’ (2012) 12 <https://www.nature.com/nri/volumes/12/issues/4>
Niemeyer CM and Kratz CP, ‘Paediatric Myelodysplastic Syndromes and Juvenile Myelomonocytic Leukaemia: Molecular Classification and Treatment Options’ (2008) 140 British Journal of Haematology 610
Niklison-Chirou MV and others, ‘TAp73 Is a Marker of Glutamine Addiction in Medulloblastoma’ (2017) 31 Genes & Development 1738
Northcott PA and others, ‘The Clinical Implications of Medulloblastoma Subgroups’ (2012) 8 Nature Reviews Neurology 340
O’Connor D and others, ‘Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia’ (2018) 36 Journal of Clinical Oncology 34
——, ‘Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia’ (2018) 36 Journal of Clinical Oncology 34
Pastorino F and others, ‘Ligand-Targeted Liposomal Therapies of Neuroblastoma’ (2007) 14 Current Medicinal Chemistry 3070
Pathania M and others, ‘H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas’ (2017) 32 Cancer Cell 684
Pfister S and others, ‘Novel Genomic Amplification Targeting the microRNA Cluster at 19q13.42 in a Pediatric Embryonal Tumor with Abundant Neuropil and True Rosettes’ (2009) 117 Acta Neuropathologica 457
Phoenix TN and others, ‘Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype’ (2016) 29 Cancer Cell 508
Qasim W and others, ‘Molecular Remission of Infant B-ALL after Infusion of Universal TALEN Gene-Edited CAR T Cells’ (2017) 9 Science Translational Medicine
Qiao J and others, ‘PI3K/AKT and ERK Regulate Retinoic Acid-Induced Neuroblastoma Cellular Differentiation’ (2012) 424 Biochemical and Biophysical Research Communications 421
Rasaiyaah J and others, ‘TCRαβ/CD3 Disruption Enables CD3-Specific Antileukemic T Cell Immunotherapy’ (2018) 3 JCI Insight
Reynolds CP and others, ‘Retinoid Therapy of High-Risk Neuroblastoma’ (2003) 197 Cancer Letters 185
Richmond A and Su Y, ‘Mouse Xenograft Models vs GEM Models for Human Cancer Therapeutics’ (2008) 1 Disease Models and Mechanisms 78
Sadelain M, Rivière I and Riddell S, ‘Therapeutic T Cell Engineering’ (2017) 545 Nature 423
Schwab M, ‘MYCN in Neuronal Tumours’ (2004) 204 Cancer Letters 179
Schwalbe EC and others, ‘Novel Molecular Subgroups for Clinical Classification and Outcome Prediction in Childhood Medulloblastoma: A Cohort Study’ (2017) 18 The Lancet Oncology 958
Schwalbe EdC and others, ‘Histologically Defined Central Nervous System Primitive Neuro-Ectodermal Tumours (CNS-PNETs) Display Heterogeneous DNA Methylation Profiles and Show Relationships to Other Paediatric Brain Tumour Types’ (2013) 126 Acta Neuropathologica 943
Schwartzentruber J and others, ‘Driver Mutations in Histone H3.3 and Chromatin Remodelling Genes in Paediatric Glioblastoma’ (2012) 482 Nature 226
Sidell N, ‘Retinoic Acid-Induced Growth Inhibition and Morphologic Differentiation of Human Neuroblastoma Cells In Vitro’ [1982] JNCI: Journal of the National Cancer Institute
Slany RK, ‘The Molecular Mechanics of Mixed Lineage Leukemia’ (2016) 35 Oncogene 5215
Stone TJ and Jacques TS, ‘Medulloblastoma: Selecting Children for Reduced Treatment’ (2015) 41 Neuropathology and Applied Neurobiology 106
Strebhardt K and Ullrich A, ‘Paul Ehrlich’s Magic Bullet Concept: 100 Years of Progress’ (2008) 8 Nature Reviews Cancer 473
Sturm D and others, ‘Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma’ (2012) 22 Cancer Cell 425
——, ‘New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs’ (2016) 164 Cell 1060
Taylor, Michael DNorthcott, Paul AKorshunov, AndreyRemke, MarcCho, Yoon-jae, ‘Molecular Subgroups of Medulloblastoma: The Current Consensus’ 123 Acta Neuropathologica 465 <https://search.proquest.com/docview/928783888?rfr_id=info%3Axri%2Fsid%3Aprimo>
Vogelstein B and others, ‘Cancer Genome Landscapes’ (2013) 339 Science 1546
——, ‘Cancer Genome Landscapes’ (2013) 339 Science 1546
Vora A and others, ‘Treatment Reduction for Children and Young Adults with Low-Risk Acute Lymphoblastic Leukaemia Defined by Minimal Residual Disease (UKALL 2003): A Randomised Controlled Trial’ (2013) 14 The Lancet Oncology 199
——, ‘Augmented Post-Remission Therapy for a Minimal Residual Disease-Defined High-Risk Subgroup of Children and Young People with Clinical Standard-Risk and Intermediate-Risk Acute Lymphoblastic Leukaemia (UKALL 2003): A Randomised Controlled Trial’ (2014) 15 The Lancet Oncology 809
Wegman-Ostrosky T and Savage SA, ‘The Genomics of Inherited Bone Marrow Failure: From Mechanism to the Clinic’ (2017) 177 British Journal of Haematology 526
Weinberg RA, The Biology of Cancer (2nd ed, Garland Science 2014)
Wright JH, ‘NEUROCYTOMA OR NEUROBLASTOMA, A KIND OF TUMOR NOT GENERALLY RECOGNIZED’ (1910) 12 The Journal of Experimental Medicine
Yang, LiqunKe, Xiao-XueXuan, FanTan, JuanHou, Jianbing, ‘PHOX2B Is Associated with Neuroblastoma Cell Differentiation’ 31 Cancer Biotherapy & Radiopharmaceuticals 44 <https://search.proquest.com/docview/1776665507?rfr_id=info%3Axri%2Fsid%3Aprimo>
Yong CSM and others, ‘CAR T-Cell Therapy of Solid Tumors’ (2017) 95 Immunology and Cell Biology 356
Zelent A, Greaves M and Enver T, ‘Role of the TEL-AML1 Fusion Gene in the Molecular Pathogenesis of Childhood Acute Lymphoblastic Leukaemia’ (2004) 23 Oncogene 4275
Zhu S and others, ‘Activated ALK Collaborates with MYCN in Neuroblastoma Pathogenesis’ (2012) 21 Cancer Cell 362
